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Original Article · Open access

Comparison of complications between total hip arthroplasty following failed internal fixation and primary total hip arthroplasty for femoral neck fractures: A meta-analysis

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Haotian Yin

Department of Joints, Tianjin Hospital of Tianjin University (Tianjin Hospital), Tianjin, China

ORCID: 0009-0001-8208-3553

Yixiang Zhang

Department of Joints, Tianjin Hospital of Tianjin University (Tianjin Hospital), Tianjin, China Clinical College of Orthopedics, Tianjin Medical University, Tianjin, China

ORCID: 0009-0007-9352-8937

Wenbo Hou

Department of Joints, Tianjin Hospital of Tianjin University (Tianjin Hospital), Tianjin, China

ORCID: 0009-0004-6361-0305

Lei Wang

Department of Joints, Tianjin Hospital of Tianjin University (Tianjin Hospital), Tianjin, China

ORCID: 0009-0009-8121-7036

Xin Fu

Department of Joints, Tianjin Hospital of Tianjin University (Tianjin Hospital), Tianjin, China

ORCID: 0000-0002-6786-9259

Jun Liu

Department of Joints, Tianjin Hospital of Tianjin University (Tianjin Hospital), Tianjin, China

ORCID: 0009-0002-8064-9856

Abstract

Objectives: In this meta-analysis, we discuss the complication rates of conversion to total hip arthroplasty (cTHA) following failed internal fixation (IF) of femoral neck fractures (FNFs) versus primary total hip arthroplasty (pTHA).

Materials and methods: The Cochrane Library, Web of Science, PubMed, Embase, and Science Direct databases were searched for eligible publications published prior to December 2024. The search terms included “femoral neck fracture”, “internal fixation failure”, and “total hip arthroplasty”. The mean difference (MD) and risk difference (RD) were used as combined variables, and 95% confidence intervals (CIs) were chosen.

Results: Six non-randomized-controlled clinical trials comprising 1,301 patients were included in this meta-analysis. The pooled data revealed statistically significant differences in postoperative deep infection rates (RD=0.04; 95% CI: 0.01- 0.08; p=0.009), periprosthetic fractures (RD=0.03; 95% CI: 0.00-0.05; p=0.03), and reoperation rates (RD=0.07; 95% CI: 0.03-0.11; p=0.0002) between the cTHA and pTHA groups. However, no significant differences were observed in the incidence of postoperative dislocations (RD=0.05; 95% CI: –0.03-0.13; p=0.19), deep vein thrombosis (RD= –0.01; 95% CI: –0.04-0.03; p=0.77), superficial infections (RD=0.02; 95% CI: –0.02-0.06; p=0.37), or revision surgeries (RD=0.02; 95% CI: –0.01-0.05; p=0.13).

Conclusion: Compared to pTHA, cTHA following failed IF of FNFs was associated with higher deep infection, periprosthetic fractures, and reoperation rates.

Declarations

Author Contributions

Contributed to conception and design of this study: H.T.Y., Y.X.Z., W.B.H., L.W., X.F., J.L.; Study selection and data extraction of the finally included studies were done independently assessed the methodological quality of each included study: by H.T.Y., Y.X.Z., W.B.H.; Contributed to preparation of the manuscript: H.T.Y., Y.X.Z., J.L. The final version of the article was approved by all the authors.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.

Data Sharing Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.