Case Report · Open access
Endobronchial pulmonary metastasis in malignant tenosynovial giant cell tumor: A rare cause of central airway obstruction
Abstract
Tenosynovial giant cell tumor (TGCT) is a rare mesenchymal neoplasm arising from the synovium, tendon sheath, or bursa. Although the localized and diffuse forms of TGCT are typically considered benign, malignant TGCT characterized by marked histologic atypia and increased mitotic activity may exhibit aggressive clinical behavior. Pulmonary metastasis from malignant TGCT is rare and, in previously reported cases, pulmonary involvement has predominantly been described as parenchymal nodules or pleural lesions. In this article, we describe a rare case of endobronchial pulmonary metastasis occurring approximately 72 months after the initial diagnosis of malignant TGCT originating from the tendon sheath of the knee.
Declarations
Author Contributions
I.C.: Idea/concept, design; M.A.O.: Control/supervision, analysis and/or interpretation; C.C., S.K.D., N.B.: Data collection and/or processing; I.C., C.C.: Literature review, writing the article; M.A.O.: Critical review; I.C., C.C., S.K.D., N.B.: References and fundings; S.K.D., N.B., M.A.O.: Materials.
Conflict of Interest
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
Financial Disclosure
The authors also acknowledge the institutional support provided by the Department of Pulmonology.
Acknowledgments
The authors thank the interventional pulmonology nurses and technical staff of Basaksehir Cam ve Sakura City Hospital for their valuable assistance during the bronchoscopic procedure.
Data Sharing Statement
The data that support the findings of this study are available from the corresponding author upon reasonable request.
AI Disclosure
The authors declare that artificial intelligence (AI) tools were not used, or were used solely for language editing, and had no role in data analysis, interpretation, or the formulation of conclusions. All scientific content, data interpretation, and conclusions are the sole responsibility of the authors. The authors further confirm that AI tools were not used to generate, fabricate, or ‘hallucinate’ references, and that all references have been carefully verified for accuracy.
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