Skip to main content
JDRS · Open access journal

Original Article · Open access

Impact of diabetes mellitus and preoperative body mass index on 30-day postoperative complications and readmissions following total knee arthroplasty

PDF Cite this article

Kwong Weng Loh

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

ORCID: 0000-0002-2307-8877

Suraya Zulkhairi

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

ORCID: 0009-0000-7343-1256

Khai Hsin Wong

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

ORCID: 0009-0000-9808-9864

Khairul Anwar Ayob

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

ORCID: 0000-0003-1651-1684

Veenesh Selvaratnam

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

ORCID: 0000-0002-3821-1781

Azlina Amir Abbas

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

ORCID: 0000-0003-4423-4653

Abstract

Objectives: This study aims to evaluate 30-day postoperative complications and hospital readmissions across different body mass index (BMI) categories and diabetic statuses following primary total knee arthroplasty (TKA).

Patients and methods: Between January 2013 and December 2022, a total of 502 patients (100 males, 402 females; mean age: 68.8±7.7 years; range, 45 to 91 years) who underwent primary TKA for knee osteoarthritis were retrospectively analyzed. Data collected included basic demography, BMI, diabetes mellitus (DM) status, and 30-day postoperative complications such as venous thromboembolism (VTE), infections, neurological events, cardiac events, and renal issues. Readmissions due to operative or medical complications were recorded.

Results: Of the patients, 141 (28.1%) had DM and 186 (37.1%) patients were classified as obese. The obese group experienced the highest incidence of VTE (1.6%), whereas overweight patients exhibited a higher rate of renal events (1.0%). All non-diabetic underweight patients (n=2) developed postoperative hypoglycemia. Diabetic patients had significantly increased odds of VTE compared to non-diabetics (odds ratio=6.74; p=0.009). Normal BMI diabetic patients demonstrated the highest incidence of surgical site infections (7.4%), while normal BMI non-diabetic patients were more prone to foot drop (1.1%) and cardiac events (4.5%).

Conclusion: Elevated BMI and DM independently or in combination, contribute to higher rates of postoperative complications and readmissions following TKA.

Declarations

Author Contributions

Designed and wrote the initial draft: L.K.W., S.Z.; Participated in data collection: S.Z., W.K.H., K.A.A., V.S.; Conducted data analysis: S.Z., W.K.H., A.A.A.; Conducted manuscript review and editing: K.A.A., V.S., A.A.A. All authors were involved in writing and reviewing the manuscript. All authors read and approved the final manuscript.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.

Data Sharing Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.